A person with chronic alcohol intake will end up with liver damage by a process which involves cytokines, oxidative and nitrosative stress, hypoxia, and alterations in energy metabolism. Kadukkai maathirai is a polyherbal Siddha preparation indicated for anemia and liver diseases. Siddha clinicians have the doubt that what type of liver diseases can be treated with Kadukkai maathirai.  So, Mr.Manjunath Shetty, a Pharmacology Lecturer from Melaka Manipal Medical College has taken a challenge to find the beneficial role of kadukkaai maathirai in different liver diseases. Alcohol drinking may lead to extensive ballooning degeneration of hepatocytes and microvesicular steatosis. Kadukkai maathirai has the capability to reduce the  alcohol induced liver damage and brings the liver near normal architecture. In the animal experiment, the important observation was the higher dose of kadukkai mathirai has its own side effects in the liver itself. His study is going on, probably, within next two years, he will complete the study and tell its usefulness in viral hepatitis, liver cancer, non alcoholic fatty liver, etc. May Siddhars give more strength and opportunity to our Manipal Siddha team for Siddha globalization through research.  - By Dr.Arul Amuthan
https://innovareacademics.in/journals/index.php/ajpcr/article/view/26773

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